1.Abstract:

Early embryonic development needs detailed investigations if we have to reduce embryonic mortality. Embryonic mortality details have been reviewed (wani, 2005). The reproductive abnormalities have been discussed and a sequential photographic presentation of embryonic mortality have recently been published (Khatoon et al 2007). The critical period when maximum embryonic losses go unnoticed is the period before attachment. Losses before actual union of foeto-maternal tissues can be missed and calculations of embryonic mortality estimates remain unaccounted for. Some recent studies of (Wani 2006, Khatoon et al 2006) have paved a new innovative model for investigation on foeto-maternal development and its attachment. This paper describes the detailed embryonic development, blastocyst elongation, formation of cotyledons within elongated blastocyst, their ramifications and networking of vasculature and formation of foetal placental unit. Conversely, a detailed photographic evidence of uterine receptivity, formation of a multicoated immunological barrier- the beginning of foeto- maternal- barrier mechanism along with caruncle formation, uterine milk formation and finally union of cotyledous with caruncles has been photographically documented.
2.Introduction:

Second and 3rd generation animal biotechnologies as reviewed (Wani, 2005) are multiple ovulation, embryo-transfer, preservation, cloning, micromanipulation splitting of embryos and nuclear transfer. The 4th Generation reproductive technologies have advance beyond our imagination and now we do have transgenic goats giving milk rich in insulin. (Wani 2007). The stem cell technology, embryonic cell culture, pronuclear micro-injection along with sperm-mediated, transgenesis have been in use and are precisely reviewed and discussed (Wani 2005, 2007).

19 October 2010
ITC Maratha, Mumbai, India

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